Abstract
Introduction: Atrial fibrillation is presented as one of the main risk factors for the presence of stroke of cardioembolic origin. Its increasing prevalence is particularly caused by the aging population growth. This type of arrhythmia requires secondary prevention compared to the treatment of other illnesses.
Objective: To describe the characteristics of ischemic stroke patients and its relationship with atrial fibrillation.
Materials and methods: Retrospective descriptive study of individuals admitted with ischemic stroke. Information of risk factors for cerebrovascular disease, presence or abscense of atrial fibrillation and treatment received was collected. Comparative tables according to the presence or absence of atrial fibrillation were performed. Values less than 0.05 were considered significant.
Results: There were 246 patients with ischemic stroke. The median of age was 71 years and half were male. The prevalence of risk factors for ischemic stroke were 73.9% for arterial hypertension (HT), 23.9% previous stroke, 20.7% for smoking. . The prevalence of atrial fibrillation was 24.3%, being higher in patients with concomitant heart failure (OR 3.5 95% CI 1.6 to 7.75 p = 0.000). There were lower probability of atrial fibrillation among men (OR 0.49 95% CI 0.26-0.92 p = 0.018). Dilatation of the left atrium was present in 43.1% ischemic stroke patients. 57% of the individuals who were taking oral anticoagulants had atrial fibrillation Only 15% met criteria for thrombolysis. The all-cause mortality in patients with ischemic stroke was 13.8% and in the atrial fibrillation group was 16%.
Conclusion: Ischemic stroke is a prevalent disease in our population and nearly one in five patients with ischemic stroke have previous atrial fibrillation or de novo diagnosed during the event. The mortality in this subgroup of patients is 16%.
References
WOLF PA, ABBOTT RD, KANNEL WB. Atrial fibrillation as an independent risk factor for stroke: the Framingham Study. Stroke 1991;22(8):983-8.
ENGDAHL J, ANDERSSON L, MIRSKAYA M, ROSENQVIST M. Stepwise screening of atrial fibrillation in a 75-year-old population: implications for stroke prevention. Circulation 2013;127(8):930-7.
WOLF PA. Atrial Fibrillation: A Major Contributor to Stroke in the Elderly The Framingham Study. Arch Intern Med. 1987;147(9):1561.
APENTENG PN, MURRAY ET, HOLDER R, HOBBS FDR, FITZMAURICE DA. An international longitudinal registry of patients with atrial fibrillation at risk of stroke (Garfield): the UK protocol. BMC Cardiovasc Disord 2013;13:31.
SILVA FA, ZARRUK JG, QUINTERO C, ARENAS W, SILVA SY. Enfermedad cerebrovascular en Colombia. Rev Colomb Cardiol. 2006;13(2):85-9.
HYLEK EM, GO AS, CHAN Y, ET AL. Effect of intensity of oral anticoagulation on stroke severity and mortality in atrial fibrillation. N Engl J Med. 2003;1019-26.
TOTH PP. Stroke prevention in patients with atrial fibrillation: Focus on new oral anticoagulants. Postgrad Med. 2013;125(3):155-61.
CASTAÑEDA C, CASAS J, RUEDA MC, ET AL. Experience with intravenous thrombolysis for stroke in the Hospital Universitario San Ignacio 2011-2013 (Extro HUSI). Acta Neurol Colomb. 2014;30:16-21.
KHATRI P, WECHSLER LR, BRODERICK JP. Intracranial hemorrhage associated with revascularization therapies. Stroke 2007;38(2):431-40.
VANDER WORP HB, VAN GIJN J. Acute Ischemic Stroke. N Engl J Med. 2007;357:572-9.
PÉREZ JC, ÁLVAREZ LC, LONDOÑO AL. Factores de riesgo relacionados con la mortalidad por enfermedad cerebrovascular, Armenia, Colombia, 2008. Iatreia 2011;24(1):26-33.
JØRGENSEN HS, NAKAYAMA H, REITH J, RAASCHOU HO OLSEN TS. Acute stroke with atrial fibrillation. The Copenhagen Stroke Study. Stroke 1996;10:1765-9.

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