Resumen
La hemostasis es un mecanismo fisiológico que mantiene la sangre en estado fluido dentro de la circulación. La coa- gulación está mediada por componentes celulares y proteínas solubles plasmáticas. En respuesta a la lesión vascular las plaquetas circulantes se adhieren, agregan y proveen una superficie celular de fosfolípidos para el ensamblaje de los complejos enzimáticos de la coagulación. Su falla puede tener consecuencias letales para los individuos. Se ha propuesto un nuevo modelo de coagulación basado en la célula, que describe mejor el proceso in vivo, de fácil comprensión para los neurólogos y mayor usada en la toma de decisiones clínicas.
Citas
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