Farmacoterapia de la acatisia aguda inducida por neurolépticos
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Palabras clave

Acatisia inducida por medicamentos
agitación psicomotora
antipsicóticos
efectos adversos
trastornos del movimiento
inducidos químicamente (DeCS)
adverse effects
chemically induced

Resumen

La acatisia aguda es un trastorno del movimiento bastante molesto, caracterizado por sensación subjetiva y signos objetivos de inquietud motora, que se presenta frecuentemente como efecto adverso de los neuroslépticos; un tratamiento oportuno es necesario para garantizar una buena adherencia al manejo con antipsicóticos y prevenir recaídas.

Se describe el estado actual de los tratamientos disponibles para la acatisia aguda inducida por neurolépticos, valorando efectividad y tolerabilidad.

Se realizó una búsqueda electrónica en Pubmed, Science Alert, Springer link, SciELO, Ovid y Elsevier con criterios de selección específicos, obteniendo 87 estudios, de los cuales se escogieron 51 teniendo en cuenta relevancia clínica, nivel de evidencia y actualidad.

En este artículo se describen los resultados de la búsqueda. Las benzodiacepinas, los betabloqueadores lipofílicos de acción central y los anticolinérgicos son los fármacos más estudiados para el tratamiento de este trastorno del movimiento; los dos primeros han mostrado superioridad, sin embargo, se necesita aún bastante investigación al respecto.

Palabras clave: Acatisia inducida por medicamentos, agitación psicomotora, antipsicóticos, efectos adversos, trastornos del movimiento, inducidos químicamente (DeCS).

https://doi.org/10.22379/2422402265%20

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