Lipid emulsion as an antidote to progressive neurological impairment after injection of high doses of local anesthetic: case report
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Keywords

Lipids
emulsion
toxic effects
local anesthetic
neuropathic pain (MeSH)

Abstract

The infiltration of local anesthetic (LA) is increasingly widespread as an indication in the treatment of neuropathic pain. AL poisoning is rare but serious, life-threatening entity and its management may be very difficult. It occurs with decreased level of consciousness, seizures and cardiac conduction blocks. The lipid emulsion (EL) 20% is the only specific treatment described to date and it has improved the prognosis of these patients. We report the case of a patient with progressive neurological deterioration after injection of high doses of LA for treat a neuropathic pain refractory to other treatments. The patient was treated with lipid emulsion 20% with reversing all the neurological symptoms early and completely. The occurrence of progressive neurological symptoms in the context of a local anesthetic infiltration, should alert us to a possible poisoning and to start early treatment with lipid emulsion 20%, to avoid poor prognosis. However, prevention remains the main tool.

https://doi.org/10.22379/2422402289

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