Abstract
Coronavirus disease 2019 (COVID-19) can be classified as asymptomatic, mild, moderate, severe, and critical according to respiratory symptoms. Thirty-six percent of its manifestations can be neurological either central, peripheral or musculoskeletal. In many countries, access to intensive care units and ventilatory devices has been limited, generating ethical dilemmas.
References
Wang Y, Wang Y Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID-19) implicate special control measures. J Med Virol. 2020;92(6):568-76.
World Health Organization. WHO statement on the meeting of the International Health Regulations Emergency Committee regarding the 2014 Ebola outbreak in West Africa. 2014. [Internet]. 2014 Disponible en: Disponible en: http://www.euro.who.int/en/health-topics/health-emergencies/ebola-outbreak-2014/tech-nical-information/ihr-emergency-committee-regarding-ebola/ who-statement-on-the-meeting-of-the-international-health-regulations-emergency-committee-regarding-the-2014-ebola-outbreak-in-west-africa
Organización Panamericana de la Salud / Organización Mundial de la Salud. La OMS caracteriza a covid-19 como una pandemia [Internet]. 2020 Disponible en: https://www.paho.org/hq/index.php?option=com_content&view=article&id= 15756:who-characterizes-covid-19-as-a-pandemic&Itemid=19 26&lang=es
Zhong N, Zheng B, Li YM, Poon Y, Xie ZH, Chan KH, et al. Epidemiology and cause of severe acute respiratory syndrome (SARS) in Guangdong, People's Republic of China, in February, 2003. Lancet 2003;362(9393):1353-8.
Cauchemez S, Van Kerkhove MD. Transmission scenarios for Middle East Respiratory Syndrome Coronavirus (MERS-CoV) and how to tell them apart. Euro Surveill. 2013;13;18(24):20503.
Wilder-Smith A, Chiew CJ. Can we contain the COVID-19 outbreak with the same measures as for SARS? Lancet Infect Dis. 2020; 20(5): e102-e107.
Chafekar A, Fielding BC. MERS-CoV: Understanding the latest human coronavirus threat. Viruses. 2018;10(2):93.
De Tomás JFA. Coronavirus covid-19; patogenia, prevención y tratamiento. Primera edición. Leioa: Salusplay; 2020.
Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet. 2020;395(10223):507-13.
Xu Z, Li S, Tian S. Full spectrum of COVID-19 severity still being depicted. Lancet. 2020;395(10228):947-8.
Li Y-C, Bai W-Z, Hashikawa T. The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients. J Med Virol. 2020;92:552-5.
Carbonell Mateu R, Carballo Aparicio KC. Electroencephalographic patterns and clinical evolution in patients with encephalopathy in intensive care unit. ALERTA Rev Científica Inst Nac Salud. 2019;2(2):153-62.
Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497-506.
Dubé M, Coupanec AL. Axonal transport enables neuron-to-neuron propagation of human coronavirus OC43. J Virol. ;2018;92(17): e00404-18.
Mao L, Wang M, Wang M, Hu Y, Chen S, He Q, et al. Neurological manifestations of hospitalized patients with COVID-19 in Wuhan, China: a retrospective case series study. medRxiv JAMA Neurol. 2020 Apr 10;e201127..
Poyiadji N, Shahin G, Noujaim D. COVID-19-associated acute hemorrhagic necrotizing encephalopathy: CT and MRI Features. Radiology. 2020:201187.
Rossi A. Imaging of acute disseminated encephalomyelitis. Neuroimaging Clin N Am. 2008;18(1):149-61.
Mehta P, McAuley DF. COVID-19: consider cytokine storm syndromes and immunosuppression. Lancet. 2020;395(10229): 1033-4
Talan J. COVID-19: Neurologists in Italy to colleagues in US: Look for poorly-defined neurologic conditions in patients with the coronavirus. Neurol Today. 2020; Disponible en: https://journals.lww.com/neurotodayonllne/blog/breakingnews/pages/post.aspx?PostID=920
Filatov A, Sharma P. Neurological complications of coro-navirus disease (COVID-19): encephalopathy. Cureus. 2020; 12(3):e7352. Disponible en: https://www.cureus.com/articles/29414-neurological-complications-of-coronavirus-disease-covid-19-encephalopathy
Yu F, Du L, Ojcius DM. Measures for diagnosing and treating infections by a novel coronavirus responsible for a pneumonia outbreak originating in Wuhan, China. Microbes Infect. 2020;22(2):74-9.
Ministerio de Salud y Protección Social. Módulos-covid-19 [Internet]. 2020. Disponible en: https://www.ins.gov.co/Direcciones/ONS/Paginas/modulos-covid-19.aspx
Organización Mundial de la salud. Consideraciones éticas en el desarrollo de una respuesta de salud pública a la gripe pandémica. [Internet]. 2007 Disponible en: https://apps.who.int/iris/handle/10665/70164
Società Italiana di Anestesia, Analgesia, Rianimazione e Terapia Intensiva (SIAARTI). Clinical ethics recommendations for the allocation of intensive care treatments in exceptional, resource-limited circumstances - Version n. 1 [Internet]. 2020 [citado 7 de abril de 2020]. Disponible en: Disponible en: http://www.siaarti.it/SiteAssets/News/COVID19%20-%20documenti%20SIAARTI/SIAARTI%20-%20Covid-19%20-%20Clinical%20 Ethics%20Reccomendations.pdf
WMinisterio de Salud y Protección Social. Recomendaciones generales para la toma de decisiones éticas en los servicios de salud durante la pandemia COVID-19 [Internet]. 2020 Disponible en: https://www.minsalud.gov.co/Ministerio/Institucional/Procesos%20y%20procedimientos/GIPS13.pdf

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
