Neurocysticercosis and epilepsy in a university hospital in Popayán, Colombia: A case series
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Keywords

Epilepsy
Helminths
Neurocysticercosis
Seizures
Taenia solium (MeSH)

Abstract

INTRODUCTION:

Neurocysticercosis is an infection of the central nervous system caused by the larval stage of the cestode Taenia solium, it has been estimated to produce up to 30% of the cases in countries where this parasitosis is endemic. The objective of this study was to determine the frequency of patients who presented epilepsy as a sequel of neurocysticercosis in a university hospital in Popayán.

MATERIALS AND METHODS:

A retrospective study was conducted with all patients with a diagnosis of neurocysticercosis who were admitted to the Hospital Universitario San José between January 2014 and December 2018 who met the inclusion criteria.

RESULTS:

We found 50 patients, 40 (80%) of which were readmitted and 37 (74%) presented epilepsy as sequela. The most affected age-group was 41 to 60 years; 48 (96%) were from the department of Cauca, especially Mercaderes, and 33 (66%) from rural areas. Convulsive syndrome was the most frequent clinical manifestation on admission. CT was the imaging technique of choice.

CONCLUSION:

The department of Cauca is considered as an endemic area for neurocysticercosis, and secondary epilepsy was a common consequence.

https://doi.org/10.22379/anc.v39i1.883

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References

García HH, Gonzáles AE, Gilman RH. Taenia solium cysticercosis and its impact in neurological disease. Clin Microbiol Rev. 2020;33(3):e00085-19.

Hotez PJ, Bottazzi ME, Paredes CF, Ault SK, Periago MR. The neglected tropical diseases of Latin America and the Caribbean: A review of disease burden and distribution and a roadmap for control and elimination. PLoS Negl Trop Dis. 2008;2(9):e300.

Welburn SC, I B, Ducrotoy MJ, Okello AL. The neglected zoonoses: The case for integrated control and advocacy. Clin Microbiol Infect. 2015;21(5):433-43.

Sarria Estrada S, Verzelli, Frascheri L, Montilva Siurana S, Auger Acosta C, Rovira Canellas A. Neurocisticercosis: hallazgos radiológicos. Radiologia. 2013;55(2):130-41.

Fernández Rodríguez R, González Fernández C, Guitián Deltell J. Neurocisticercosis: una enfermedad que no debemos olvidar. Galicia Clin. 2017;78(3):116-22.

Velasquez Salazar R, Rojas S, Briceño A, Prieto M. Neurocisticercosis: enfermedad infecciosa desatendida, olvidada y emergente. A propósito de un caso. Comunidad y Salud. 2016;14(2)14-23.

Zapata CH, Vargas SA, Uribe CS. Neurocisticercosis racemosa (sic), diagnóstico orientado por neuroimágenes. Biomédica. 2017;37(Supl. 1):26-32.

San-Juan Orta D, Rodríguez Zubia E, Gómez González GJ, Vázquez Gregorio R, Tabera Tarello PM, Fleury A. Neurocis ticercosis y epilepsia. An Med. 2014;59(3):212-8.

Del Brutto OH, Nash TE, White Jr AC, Rajshekhar V, Wilkins PP, Singh G, et al. Revised diagnostic criteria for neurocysticercosis. J Neurol Sci. 2017;372:202-10.

Vásquez Arteaga LR, Zamora Bastidas TO, Vivas Velásco VH, Giraldo Forero JC, Casas-Zúñiga JC. Epidemiología de la cisticercosis humana en pacientes de consulta neurológica en Popayán, Cauca, Colombia. Medicina (B Aires). 2016;38(4):305-15.

Flisser A. Control de la teniasis y la cisticercosis en México. Biomédica. 2011;31(Sup. 3):3-315.

Fleury A, Escobar A, Fragoso G, Sciutto E, Larralde C. Clinical heterogeneity of human neurocysticercosis results from complex interactions among parasite, host and environmental factors. Trans R Soc Trop Med Hyg. 2010;104(4):243-50.

Flórez Sánchez AC, Pastrán SM, Vargas NS, Beltrán M, Enriquez Y, Peña AP, et al. Cisticercosis en Colombia. Estudio de seroprevalencia 2008 - 2010. Acta Neurol Colomb. 2013;29(2):73-86.

Toquero M, Morocoima A, Ferrer E. Seroprevalencia y factores de riesgo de cisticercosis en dos comunidades rurales del norte del estado Anzoátegui, Venezuela. Biomédica. 2016;37(Supl. 1):66-74.

Rosselli D, Pantoja-Ruiz C. La neurocisticercosis en Colombia: otra enfermedad desatendida. Acta Neurol Colomb. 2023;39(1): 2-5:

Pal DK, Carpio A, Sander JW. Neurocysticercosis and epilepsy in developing countries. J Neurol Neurosurg Psychiatry. 2000;68(2):137-43.

Carabin H, Ndimubanzi PC, Budke CM, Nguyen H, Qian Y, Linda, et al. Clinical manifestations associated with neu-rocysticercosis: A systematic review. PLoS Negl Trop Dis. 2011;5(5):e1152.

Del Brutto OH. Neurocysticercosis. Continuum (N Y). 2012;18(6):1392-416.

Gripper LB, Welburn SC. The causal relationship between neurocysticercosis infection and the development of epilepsy: A systematic review. Infect Dis Poverty. 2017;6(1):31.

Kimura-Hayama ET, Higuera JA, Corona-Cedillo R, Chávez-Macías L, Perochena A, Quiroz-Rojas LY, et al. Neurocysticercosis: Radiologicpathologic correlation. RadioGraphics. 2010;30(6):1705-19.

Kelvin EA, Carpio A, Bagiella E, Leslie D, Leon P, Andrews H, et al. Seizure in people with newly diagnosed active or transitional neurocysticercosis. Seizure. 2011;20(2):119-25.

Coyle CM. Neurocysticerosis: An individualized approach. Infect Dis Clin North Am. 2019;33(1):153-68.

Garcia HH, Castillo Y, Gonzales I, Bustos JA, Saavedra H, Jacob L, et al. Low sensitivity and frequent cross-reactions in commercially available antibody detection ELISA assays for Taenia solium cysticercosis. Trop Med Int Health. 2018;23(1):101-5.

Vásquez-Arteaga LR, Giraldo-Forero JC. Public policy for controlling the taeniasis/cysticercosis complex in Colombia. Case Reports. 2020;6(1):5-7.

Soto-Cossio E, Vicente-Hernández B, Pacheco G, Méndez-Rosito D. Neurocisticercosis ventricular: manejo multimodal y revisión de la bibliografía. Med Int Méx. 2018;34(5):797-803.

Campos Paiva AL, Vitorino Araujo JL, Ferraz VR, Lovato RM, Grander Pedrozo CA, Aguiar, Brasileiro de G, et al. Surgical treatment of neurocysticercosis. Retrospective cohort study and an illustrative case report. Sao Paulo Med. 2017;135(2):146-9.

Carpio A, Chang M, Zhang H, Romo ML, Jaramillo A, Hauser WA, et al. Exploring the complex associations over time among albendazole treatment, cyst evolution, and seizure outcomes in neurocysticercosis. Epilepsia. 2019;60(9):1820-8.

Nash TE, Mahanty S, Garcia HH. Corticosteroid use in neurocysticercosis. Expert Rev Neurother. 2011;11(8):1175-83.

Matthaiou DK, Panos G, Adamidi ES, Falagas ME. Albendazole versus praziquantel in the treatment of neurocysticercosis: A meta-analysis of comparative trials. PLoS Negl Trop Dis. 2008;2(3):e194.

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