Abstract
To describe Cutis Verticis gyrate (CVG) in cases found in an institutionalized people facility in Colombia. Case series with 65 male adult in-patients, describing socio-demographic and clinical variables. Prevalence of 5.9 % was higher than expected in the general population (1:100.000 in males). Mean age: 38.5 years, most illiterate (98.46%). The most frequent diagnosis was profound mental retardation in 59 (90.77 %) cases, with high multi-axis comorbidity. Folds range from 1 to 16. Age of onset and type of CVG couldn't be established.
This is the largest case series reported from a single institution. There is need of further study to determine type, origin, and evolution of the sign.
References
Akesson HO. Cutis verticis gyrata and mental deficiency in Sweden. I Acta Med. Scand. 1964:115-128. 175, 1.
Diven D, Tanus T, Raimer SS. Cutis Verticis Gyrata. International Journal of Dermatology, October 1991, 30, No 10 710-12.
Akesson HO. Cutis verticis gyrata and mental deficiency in Sweden. II. Genetic aspects. Acta Med. Scand. 1965:459-464.
Garden J, Robinson JK. Essential primary Cutis Verticis Gyrata. Treatment with the scalp reduction procedure. Arch Dermatol. 120 Nov 1984.
Polan S, Buttenwort T, 1953 Am J Ment Defic. Cutis verticis gyrata; a review with report of seven new cases. 1953 Apr; 57(4):613-31.
Rosso Schons KR, Costa Beber AA. Cutis Verticis Gyrata. N Engl J Med 2012; 367:e23 October 18, 2012.
Cribier B, LipsKer D, Mutter D, Grosshands E. Cutis verticis gyrata: reduction surgical treatment. Ann Dermal Verereol 1993; 120:542-5.
Schepis C, Romano C. Cutaneous findings in the mentally retarded. Review. International Journal of Dermatology, 35:5, may 1996.
Schepis C. Siragusa M. Primary Cutis verticis gyrata or Pachydermia verticis gyrata: A Peculiar Scalp Disorder of Mentally Retarded Adult Males. Dermatology. 191. 4, 1995.
David TJ, Osborne CM, Research Article. Scalp hair patterns in mental subnormality. J Med Genet 1976; 13:123-126.
Tani, T; Miyamoto, Y; and Kurozumi, N. Surgical treatment of cutis verticis gyrata: A report of two cases. Br. J. Plas. Surg. 30:235, 1997.
Mégarbané A, Waked N, Chouery E, Moglabey YB, Saliba N, Mornet E, Serre JL, Slim R. Mycrocefaly, CVG of the scalp, retinitis pigmentosa, cataracts, sensorioneural deafness, mental retardation in 2 brothers. Am J Med Genet 2001:98:244-9.
Striano S, Ruosi P, Guzzeta V, Perone L, Manto A, Cirillo S. Mental Deficiency Syndrome: A Patient with Drug-Resistant Epilepsy and Polymicrogyria Epilepsia, 37(3):284-286, 1996.
Filosto M, Tonin P, Vattemi G, Bongiovanni LG, Rizzuto, N, Tomelleri, G. Cutis verticis gyrata, mental retardation and Lennox-Gastaut síndrome. Neurol Sci (2001) 22: 253-256.
Bryan D. Hall, Ronald G. Cadle, Mahin Golabi, Colleen A. Morris, Dr. M. Michael Cohen Jr. Beare-Stevenson cutis gyrata syndrome. American Journal of Medical Genetics. 44:1 (82-89), 1 September 1992.
Akai T, Lizuka H, Kishibe M, Kawakami S, Kobayashi A, Ozawa T; A case of Beare-Stevenson Cutis gyrata syndrome confirmed by mutation analysis of the fibroblast growth factor receptor 2 gene. Pediatric Neurosurgery; aug 2002.
Larsen F, Birchall N; Cutis verticis gyrata: three cases with different etiologies that demonstrate the classification system. Australasian Journal of Dermatology (2007) 48, 91-94.
Skibinska http://temedicine.medscape.com/article/1113735-treatment#a1128.
Thomson J, MacGillivray RC. Cutis Verticis Gyrata with foreign body granulomata. British Journal of Dermatology. 81: 10 (766-768), October 1969.
Al-Bedais M, Sultan AK. Acromegaly presenting as cutis verticis gyrata. International journal of Dermatology 2008, 47, 164.
Malgorzata D Skibinska M., Janniger C., Cutis Verticis gyrata. Emedicine from Wed. MED, Jan 23 2007.
Rimoin DL. Pachydermoperiostosis (idiopathic clubbing and periosis): Genetic and physiologic considerations. N. Engl. J. Med. 272; 923, 1965.
Nguyen, KH, Marks JG. Pseudoacromegaly induced by the long-term use of minoxidil. J Am Acad Dermatol 2003; 48: 692-5.
Rahman A, Mahmood A. Cutis Verticis Gyrata Secondary to Infiltrating Ductal Carcinoma Breast. Journal of the College of Physicians and Surgeons Pakistan 2012, 22 (2): 120-122.
Holbrook, Karen A, Wolff, K. Estructura y desarrollo de la piel en Fitzpatrick, T. Dermatología en medicina general, 3a ed. Editorial Panamericana, Bogotá, 1988.
Larralde M, Gardner SS, Torrado M, Fernhoff P, Santos Muñoz A, Spraker M, Sybert V. Lymphedema as a postulated cause of Cutis Verticis Gyrata in Turner Syndrome. Pediatric Dermatology. 15, 1 18-22 1998.
Parolin Marinoni L, Taniguchi K, Giraldi S, Carlvalho VO, Furucho M, Bertogna J. Cutis verticis gyrate in a child with Turner Syndrome. Pediatr Dermatol 16: 242-243, 1999.
Keller K, Williams C, Seagle B. Klinefelter syndrome and Cutis Verticis Gyrata. American Journal of medical genetics 103:249-251 (2001).
Hsieh Hl, Fisher DE, Bronson DM, Fretzin DF. Cutis verticis gyrata en neonatos. Pediatr Dermatol 1983; 1983:153-6.
Palo J, Iivanainen M, Blomqvist K, Pesonen S. Etiological aspects of the Cutis Verticis Gyrata and Mental Retardation Syndrome. Journal of Intellectual Disability Research. 14, 1: (33-43), March 1970.
Hurtado PM, Pachajoa H. Imágenes en Medicina. Cutis verticis gyrata. MEDICINA (Buenos Aires) 2012; 72: 132.
Tan O, Eegen, D. Primary essential Cutis Verticis Gyrata in an adult female patient: a case report. The journal of dermatology, 33, 7: (492-495), july, 2006.
Tani, T; Miyamoto, Y; and Kurozumi, N. Surgical treatment of cutis verticis gyrata: A report of two cases. Br. J. Plas. Surg. 30:235, 1997.
Casals J., Chinelli P., Piquero V. Pereira G. Fortes A. Cutis vértices gyrata como manifestación clínica de paquidermoperiostosis. Localizador Web 03- 046.
Masson P, Fayton M, Lamireau T, Lacombre D, Taieb A, et al, Unusual form of Noonan syndrome: neonatal muti-organ involvement with chilothorax and nevoid CVG. Pediatrics 1993: 48: 59-62.
Alorainy, IA. Magnetic Resonance Imaging of Cutis Verticis Gyrata. J Comput Assist Tomogr. 32, 1, January/February 2008.
Synder, M. Jhonson P. Hollins R. Congenital primary cutis verticis gyrata. Case report. Plastic & Reconstructive Surgery: September 1, 2002 - 110, 3: (818-821).
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