Francisco Javier Lopera Restrepo (June 10, 1951 - September 10, 2024)
PDF (Español)
XML (Español)

Keywords

Alzheimer Disease
Parkinson disease (MeSH)
Neurodegenerative Diseases
Biomedical Research
Neurology
Neurologists
Dementia
Frontotemporal Dementia
Cure in Homeopathy

Abstract

The life of Francisco Javier Lopera Restrepo, Pacho, could be summarized in the lyrics of a French song, in the verses of a local poet or in a few invented aphorisms. That cold Sunday of June 10, 1951, in the village of Aragón, municipality of Santa Rosa de Osos, towards the north of Antioquia and on the banks of the first stretch of the Rio Grande riverbed, Francisco Javier, son of Blanca Elena and Luis Emilio, was born. He was the fourth child born to Blanca Elena and was the eldest of the boys. The Lopera-Restrepo family, a typical Antioquian peasant family of 13 siblings and Aragon, a frozen land, with scarcely 700 inhabitants at that time. Between wooded mountains and the whistles of the blackbirds, at more than 2600 meters above sea level, the fog and the cold were persistent. In spite of the very low temperatures, snow did not fall, only frosts that covered the orchards with hail and destroyed the potato crops, in the dry season, and from one day to the next, ruin came.

https://doi.org/10.22379/anc.v40i4.1261

PDF (Español)
XML (Español)

References

Instituto Tecnológico Metropolitano. Desde la biblioteca: Francisco Lopera. Medellín: Instituto Tecnológico Metropolitano (ITM); 2016. Volumen 51.

Bustamante J, Lopera F, Rojas J. El Lenguaje. Medellín: Editorial Prensa Creativa; 1987.

Cornejo W, Lopera F, Uribe CS, Salinas M. Descripción de una familia con demencia presenil tipo Alzheimer. Acta Med Colomb. 1987;12(2):55-61.

Lopera Restrepo FJ, Arcos Burgos OM, Madrigal Zapata LS, Kosic K, Cornejo Ochoa JW, Ossa Londoño JE. Demencia tipo Alzheimer con agregación familiar en Antioquia, Colombia. Acta Neurol Colomb. 1994;10(4):173-187.

Lopera F, Ardilla A, Martínez A, Madrigal L, Arango-Viana JC, Lemere CA, et al. Clinical features of early-onset Alzheimer disease in large kindred with an E280A presenilin-1 mutation. JAMA. 1997;277(10):793-9.

Reiman EM, Pruzin JJ, Rios-Romenets S, Brown C, Giraldo M, Acosta-Baena N, et al. A public resource of baseline data from the Alzheimer's Prevention Initiative Autosomal-Dominant Alzheimer's Disease Trial. Alzheimers Dement. 2023;19(5):1938-46. https://doi.org/10.1002/alz.12843

Arboleda-Velasquez JF, Lopera F, O'Hare M, Delgado-Tirado S, Marino C, Chmielewska N, et al. Resistance to autosomal dominant Alzheimer's disease in an APOE3 Christchurch homozygote: a case report. Nat Med. 2019;25(11):1680-3. https://doi.org/10.1038/s41591-019-0611-3

Lopera F, Marino C, Chandrahas AS, O'Hare M, Villalba-Moreno ND, Aguillon D, et al. Resilience to autosomal dominant Alzheimer's disease in a Reelin-COLBOS heterozygous man. Nat Med. 2023;29(5):1243-52. https://doi.org/10.1038/s41591-023-02318-3

Quiroz YT, Aguillon D, Aguirre-Acevedo DC, Vasquez D, Zuluaga Y, Baena AY, et al. APOE3 Christchurch Heterozygosity and Autosomal Dominant Alzheimer's Disease. N Engl J Med. 2024;390(23):2156-64. https://doi.org/10.1056/nejmoa2308583

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Downloads

Download data is not yet available.