Abstract
Dengue virus infection is extremely common worldwide, countries like Colombia have high incidence rates for dengue. Although neurological involvement is not very common, various forms of manifestations have been described at the level of the nervous system, both central and peripheral. These have begun to constitute clearly recognized nosological forms, such as encephalitis, acute disseminated encephalomyelitis, and cerebrovascular disease. For this reason, for the clinician it is essential to know them, because some of these conditions require specific and prompt therapeutic interventions.
References
Guzman MG, Gubler DJ, Izquierdo A, Martínez E, Halstead SB. Dengue infection. Rev Dis Primers. 2016;2:16055. doi: 10.1038/nrdp.2016.55.
Castellanos J, Bello J. Manifestaciones neurológicas durante la infección por el virus del dengue. Infectio. 2014;18(4):167-76. doi: 10.1016/j.infect.2014.02.006.
Christian E. Melgar CE, González G. Neurological manifestation of dengue virus fever. Acta Neurol Colomb. 2007; 23:259-65.
Estofolete CF, Tasso de Olivera M, Bernardes T, Golcalves Aguilar BE , Rocha M, Nunes DV, et al. Unusual clinical manifestations of dengue disease - Real or imagined ? Acta Tropica. 2019;105-34. doi: 4. 10.1016/j.actatropica.2019.105134.
Ngono AE, Shresta S. Immune response to dengue and zika. Annu Rev Immunol. 2018;36:279-308. doi: 10.1146/annurev-immunol-042617-053142.
Khetarpal N, Khanna I. Dengue fever: causes, complications, and vaccine strategies. J Immunol Res. 2016;2016:6803098. doi: 10.1155/2016/6803098.
Solomon T, Dung NM, Vaughn DW, Kneen R, Thao LT, Raengsakulrach B, et al. Neurological manifestations of dengue infection. Lancet. 2000;355(9209):1053-9. doi: 10.1016/S0140-6736(00)02036-5.
Puccioni-Sohler, Rosadas C, Cabral-Castro MJ. Neurological complications in dengue infection: a review for clinical practice. Arq Neuro-Psiquiatr. 2013;71(9B):667-71. 8. doi.: 10.1590/0004-282X20130147.
Muller DA, Depelsenaire AC, Young PR. Clinical and laboratory diagnosis of dengue virus infection. J Infect Dis. 2017;215(Suppl 2): S89-S95. doi: 10.1093/infdis/jiw649.
Li GH, Ning ZJ, Liu YM, Li XH. Neurological manifestations of dengue infection. Front Cell Infect Microbiol. 2017;7:449. doi: 10.3389/fcimb.2017.00449.
Padilla-Docal B, Iglesias-González IM, Martínez-Larrarte JP, González-Losada C, Dorta-Contreras AJ. Proceso neuroinflamatorio en pacientes con el virus del dengue. Rev Neurol 2017;64:188-90. 11. doi: 10.33588/rn.6404.2016422.
World Health Organization (WHO). Dengue haemorrhagic fever and dengue shock syndrome in the context of the integrated management of childhood illness. WHO; 2005.
Wilder-Smith A, Ooi EE, Horstick O, Wills B. Dengue. Lancet. 2019;393(10169):350-63. doi: 10.1016/S0140-6736(18)32560-1.
Lin RJ, Lee TH, Leo YS. Dengue in the elderly: a review. Expert Rev Anti Infect Ther. 2017;15(8):729-35. doi: 10.1080/14787210.2017.1358610.
González GM, Amaya E, Vargas P. Características clínicas, complicaciones y secuelas de pacientes con diagnóstico de encefalitis en el hospital universitario Hernando Moncaleano Perdomo. Acta Neurol Colomb. 2014;30(3):163-8.
Mello CDS, Cabral-Castro MJ, Silva de Faria LC, Peralta JM, Puccioni-Sohler M. Dengue and chikungunya infection in neurologic disorders from endemic areas in Brazil. Neurol Clin Pract. 2020;10(6):497-502. doi: 10.1212/CPJ.0000000000000776.
González G, Galvan A, Zabaleta MP, Vargas N. Síndrome de Guillain Barré causado por el virus del dengue: a propósito de dos casos. Acta Neurol Colomb. 2015;31(1):54-9.
Parra V, Lizarazo J, Jiménez JA, Vera AFZ, González GM, Vargas J, et al. Guillain-Barré syndrome associated with zika virus infection in Colombia. N Engl J Med. 2015;375:1513-23. doi: 10.1056/NEJMoa1605564.
de Silva NL, Weeratunga P, Umapathi T, Malavige N, Chang T. Miller Fisher syndrome developing as a parainfectious manifestation of dengue fever: a case report and review of the literature. J Med Case Rep. 2019;13(1):120. doi: 10.1186/s13256-019-2066-z.
Khoo CS. Dengue cerebellitis: a case report and literature review. Am J Case Rep. 2018;19:864-7. doi: 10.12659/AJCR.909884.
Carod-Artal FJ. Complicaciones neurológicas asociadas a la infección por el virus del dengue. Rev Neurol. 2019;69:113-22. doi: 21. 10.33588/rn.6903.2019140.
Domingues RB, Kuster GW. Diagnosis and management neurologic manifestations associated with acute dengue virus infection. J Neuroinfect Dis. 2014;5(138):1-5. doi: 10.4172/2314-7326.1000138.
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.