Abstract
Migraine is a common neurological disorder affecting 13.8 per cent of the colombian women and 4.8 per cent of the colombian men. The International Classification of Headache Disorders, 2nd Edition 2004, groups headache disorders into primary and secondary headaches. Migraine is included into one of four categories of primary headaches (the others are tension-type headache, cluster headache and other trigeminal autonomic cephalalgias). In this 2nd edition of the classification, there is a restructuring of criteria for migraine with aura, chronic migraine has been added and ophthalmolplegic migraine is now considered a cranial neuralgia.
There is increasing evidence that migraine is a complex genetic disorder. Two distinct single gene defects may account for familial hemiplegic migraine, a rare autosomal dominantly inherited form.
Migraine has long been considered a risk factor for stroke since the two conditions share some physiopathogenic mechanisms such as regional changes in cerebral blood flow, platelet hyperagregability, andendothelial alterations. The widespread use of transesophageal echocardiography (TEE) has made possible to focus on the association between some cardiac abnormalities (patent foramen ovale and atrial septal aneurysm) and cerebral ischemic events. There is a hot controversy about the management of these findings and it would be necesary to waif for the results of further well-designed studies regarding the clinical characteristics of migraine attacks in relation to the right-to-left shunt opened and when it has been closed
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