Ausencia de asociación entre obesidad y sobrepeso con enfermedad cerebrovascular isquémica aguda en una muestra de población colombiana

Autores/as

  • Federico Arturo Silva S. Fundación Cardiovascular de Colombia
  • Ronald G. García Goméz Fundación Cardiovascular de Colombia.
  • Gustavo Adolfo Díaz S Fundación Cardiovascular de Colombia
  • Juan Guillermo Zarruk S Fundación Cardiovascular de Colombia
  • Cristian Federico Rueda-Clausen Fundación Cardiovascular de Colombia
  • Jorge Alberto Restrepo Hospital Santa Clara
  • Alfonso Córdoba Porras Universidad de Antioquia.

Palabras clave:

Accidente cerebrovascular, obesidad, sobrepeso, análisis multivariado

Resumen

Introducción. El sobrepeso y la obesidad han sido postulados como factores de riesgo para enfermedad coronaria, sin embargo, los estudios epidemiológicos han mostrado resultados contradictorios acerca de la asociación de estos factores con el riesgo de desarrollar enfermedad cerebrovascular isquémica aguda (ECV).

Materiales y métodos. La presente investigación es un subanálisis del análisis nacional multicéntrico de casos y controles para el estudio Factores de riesgo de enfermedad cerebrovascular isquémica en Colombia (FREC-VI). Se incluyó una muestra de 253 pacientes con diagnóstico confirmado de ECV y 253 controles. Se propuso como objetivo evaluar la asociación entre la obesidad y el sobrepeso con el riesgo de desarrollar ECV isquémica aguda ajustando por la presencia de posibles factores confusores, mediante la aplicación de una regresión logística múltiple.

Resultados. Los casos presentaron una media menor de IMC (24,90 ± 3,77 kg/m2 vs. 25,87 ± 4,25 kg/m2; p = 0,0091), además de una menor proporción de obesidad (7,51% vs. 15,05%; p = 0,010) en comparación con los controles. En el análisis crudo la obesidad mostró tendencia hacia la asociación como factor protector, no obstante, al realizar el ajuste mediante el análisis multivariado tanto el sobrepeso como la obesidad no mostraron significancia.

Conclusiones. La presencia de sobrepeso u obesidad no mostró asociación con el hallazgo de ECV isquémica aguda en una muestra de población colombiana.

Biografía del autor/a

Federico Arturo Silva S., Fundación Cardiovascular de Colombia

MD, MSc. Grupo Ciencias Neurovasculares - Fundación Cardiovascular de Colombia.

Ronald G. García Goméz, Fundación Cardiovascular de Colombia.

MD, PhD. Grupo Ciencias Neurovasculares - Fundación Cardiovascular de Colombia.

Gustavo Adolfo Díaz S, Fundación Cardiovascular de Colombia

MD; Grupo Ciencias Neurovasculares - Fundación Cardiovascular de Colombia.

Juan Guillermo Zarruk S, Fundación Cardiovascular de Colombia

MD, PhD., Grupo Ciencias Neurovasculares - Fundación Cardiovascular de Colombia.

Cristian Federico Rueda-Clausen, Fundación Cardiovascular de Colombia

MD, PhD. Grupo Ciencias Neurovasculares - Fundación Cardiovascular de Colombia.

Jorge Alberto Restrepo, Hospital Santa Clara

MD. Hospital Santa Clara, Bogotá.

Alfonso Córdoba Porras, Universidad de Antioquia.

PhD. Universidad de Antioquia.

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Cómo citar

Arturo Silva S., F., García Goméz, R. G., Díaz S, G. A., Zarruk S, J. G., Rueda-Clausen, C. F., Restrepo, J. A., & Córdoba Porras, A. (2010). Ausencia de asociación entre obesidad y sobrepeso con enfermedad cerebrovascular isquémica aguda en una muestra de población colombiana. Acta Neurológica Colombiana, 26(2), 65–74. Recuperado a partir de https://actaneurologica.com/index.php/anc/article/view/1516

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10-05-2010

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