Abstract
Introduction: there is a strong association between migraine and mood disorders, which could lead to greater disability and poorer prognosis in these patients.
Objective: to evaluate the impact of symptoms of anxiety and depression on the degree of disability in patients with migraine.
Materials and Methods: we selected 50 people with migraine (25 with aura and 25 without aura) and 25 healthy controls matched for age and sex. We measured symptoms of depression and anxiety using Zung scales. In patients with migraine was measured the degree of disability using the Headache Impact Test (HIT-6). The association between score and Zung scales HIT-6 was analyzed using linear regression.
Results: the diagnosis of migraine was significantly associated with higher scores on the depression scale (39.2 ± 10 vs 31.9 ± 6.8, p = 0.002) and anxiety (36.7 ± 10.2 vs 28.5 ± 6.7, p = 0.0001) of Zung. In patients with migraine, we found a significant association between the score of the scales of depressive symptoms (OR, 3.53, CI 95% 1.33 to 5.72, p = 0.002) and anxiety (OR, 3, 47, CI 95%, 1.33 to 5.61, p = 0.002) with the degree of disability (HIT-6). These associations remained after adjusting for age, sex and frequency of migraine episodes.
Conclusions: migraine is associated with increased presence of symptoms of anxiety and depression. This association has a negative impact on the functionality of people with this condition.
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